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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D9B All Species: 9.39
Human Site: S933 Identified Species: 22.96
UniProt: Q66K14 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q66K14 NP_055858.2 1250 140498 S933 L H L P P A L S P E E A E S A
Chimpanzee Pan troglodytes XP_001139147 1448 162825 S1122 M H V L P E P S S D Q D E P D
Rhesus Macaque Macaca mulatta XP_001090502 1222 138535 S896 M H V L P E P S S D Q D E P D
Dog Lupus familis XP_538581 1558 172372 S1235 L H L P P A L S P E E A E S A
Cat Felis silvestris
Mouse Mus musculus Q5SVR0 1263 141761 I934 L H L P P A L I P E E A E S A
Rat Rattus norvegicus NP_001101744 1262 141849 I934 L H L P P A L I P E E A E S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506944 844 94353 R568 D P T S L E E R E G A G N G D
Chicken Gallus gallus XP_414602 1261 143708 N938 L H L P P A L N P E E T E S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0W9 1108 126719 L833 L A R S A F H L L D E N G D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53258 950 109241 E675 E G L L L L T E P W K S G R Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.3 61.4 74.5 N.A. 91.7 91.5 N.A. 53.6 79.2 N.A. 46.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 66.5 74 76.1 N.A. 94.6 94 N.A. 59.2 87.2 N.A. 63.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 26.6 100 N.A. 93.3 93.3 N.A. 0 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 53.3 100 N.A. 93.3 93.3 N.A. 0 93.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 50 0 0 0 0 10 40 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 30 0 20 0 10 30 % D
% Glu: 10 0 0 0 0 30 10 10 10 50 60 0 70 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 10 0 10 20 10 10 % G
% His: 0 70 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 60 0 60 30 20 10 50 10 10 0 0 0 0 0 0 % L
% Met: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 0 % N
% Pro: 0 10 0 50 70 0 20 0 60 0 0 0 0 20 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 10 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 20 0 0 0 40 20 0 0 10 0 50 0 % S
% Thr: 0 0 10 0 0 0 10 0 0 0 0 10 0 0 0 % T
% Val: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _